*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : BU2697000
CHEMICAL NAME           : Amphotericin B, N-D-lysyl-, methyl ester
CAS REGISTRY NUMBER     : 76023-48-8
LAST UPDATED            : 198909
DATA ITEMS CITED        : 1
MOLECULAR FORMULA       : C54-H87-N3-O18
MOLECULAR WEIGHT        : 1066.44
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * Amphotericin B, N-(2,6-diamino-1-oxohexyl)-, methyl ester, (3'(R))-
   * N-D-Lysylamphotericin B methyl ester
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 38 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   JANTAJ Journal of Antibiotics.  (Japan Antibiotics Research Assoc., 2-20-8
   Kamiosaki, Shinagawa-ku, Tokyo, 141, Japan)  V.2-5, 1948-52;  V.21- 1968-
   Volume(issue)/page/year: 35,911,1982
 
                            *** END OF RECORD ***