*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : BT4200000
CHEMICAL NAME           : Ammonium, trimethyl(2-(2,6-xylyloxy)ethyl)-, bromide
CAS REGISTRY NUMBER     : 669-49-8
LAST UPDATED            : 199309
DATA ITEMS CITED        : 3
MOLECULAR FORMULA       : C13-H22-N-O.Br
MOLECULAR WEIGHT        : 288.27
WISWESSER LINE NOTATION : 1K1&1&2OR B1 F1 &Q &E
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * Choline 2,6-xylyl ether bromide
   * Ethanaminium, 2-(2,6-dimethylphenoxy)-N,N,N-trimethyl-, bromide
   * TM 10
   * Trimethyl(2-(2,6-xylyloxy)ethyl)ammonium bromide
   * Xylocholine
   * Xylocholine bromide
   * 2,6-Xylyl ether bromide
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 95 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   BJPCAL British Journal of Pharmacology and Chemotherapy.  (London, UK)
   V.1-33, 1946-68.  For publisher information, see BJPCBM.
   Volume(issue)/page/year: 9,471,1954
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 240 mg/kg
TOXIC EFFECTS :
   Behavioral - convulsions or effect on seizure threshold
   Behavioral - muscle weakness
   Lungs, Thorax, or Respiration - respiratory depression
REFERENCE :
   BJPCAL British Journal of Pharmacology and Chemotherapy.  (London, UK)
   V.1-33, 1946-68.  For publisher information, see BJPCBM.
   Volume(issue)/page/year: 12,312,1957
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 8500 ug/kg
TOXIC EFFECTS :
   Behavioral - convulsions or effect on seizure threshold
   Behavioral - muscle weakness
   Lungs, Thorax, or Respiration - respiratory depression
REFERENCE :
   BJPCAL British Journal of Pharmacology and Chemotherapy.  (London, UK)
   V.1-33, 1946-68.  For publisher information, see BJPCBM.
   Volume(issue)/page/year: 12,312,1957
 
                            *** END OF RECORD ***