*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : BS4500000
CHEMICAL NAME           : Ammonium sulfate (2:1)
CAS REGISTRY NUMBER     : 7783-20-2
LAST UPDATED            : 199710
DATA ITEMS CITED        : 11
MOLECULAR FORMULA       : O4-S.2H4-N
MOLECULAR WEIGHT        : 132.16
WISWESSER LINE NOTATION :  Z&2 S-O4
COMPOUND DESCRIPTOR     : Agricultural Chemical
                          Mutagen
                          Human
SYNONYMS/TRADE NAMES :
   * Actamaster
   * Ammonium sulphate
   * Diammonium sulfate
   * Diammonium sulphate
   * Dolamin
   * Mascagnite
   * Sulfatom ammoniya
   * Sulfuric acid, diammonium salt
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Human - man
DOSE/DURATION           : 1500 mg/kg
TOXIC EFFECTS :
   Gastrointestinal - hypermotility, diarrhea
   Gastrointestinal - nausea or vomiting
   Gastrointestinal - other changes
REFERENCE :
   GISAAA Gigiena i Sanitariya.  For English translation, see HYSAAV.  (V/O
   Mezhdunarodnaya Kniga, 113095 Moscow, USSR)  V.1-    1936-
   Volume(issue)/page/year: 42(2),100,1977
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 2840 mg/kg
TOXIC EFFECTS :
   Behavioral - somnolence (general depressed activity)
   Behavioral - muscle contraction or spasticity
   Lungs, Thorax, or Respiration - other changes
REFERENCE :
   GISAAA Gigiena i Sanitariya.  For English translation, see HYSAAV.  (V/O
   Mezhdunarodnaya Kniga, 113095 Moscow, USSR)  V.1-    1936-
   Volume(issue)/page/year: 53(2),93,1988
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 640 mg/kg
TOXIC EFFECTS :
   Behavioral - somnolence (general depressed activity)
   Behavioral - muscle contraction or spasticity
   Lungs, Thorax, or Respiration - other changes
REFERENCE :
   GISAAA Gigiena i Sanitariya.  For English translation, see HYSAAV.  (V/O
   Mezhdunarodnaya Kniga, 113095 Moscow, USSR)  V.1-    1936-
   Volume(issue)/page/year: 53(2),93,1988
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 610 mg/kg
TOXIC EFFECTS :
   Behavioral - tremor
   Behavioral - convulsions or effect on seizure threshold
   Lungs, Thorax, or Respiration - dyspnea
REFERENCE :
   UCPHAQ University of California, Berkeley, Publications in Pharmacology.
   (Berkeley, CA)  V.1-3, 1938-57.  Discontinued.  Volume(issue)/page/year:
   2,1,1941
 
TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Mammal - domestic
DOSE/DURATION           : 3500 mg/kg
TOXIC EFFECTS :
   Sense Organs and Special Senses (Eye) - mydriasis (pupillary dilation)
   Behavioral - tremor
   Lungs, Thorax, or Respiration - respiratory stimulation
REFERENCE :
   AJVRAH American Journal of Veterinary Research.  (American Veterinary
   Medical Assoc., 930 N. Meacham Rd., Schaumburg, IL 60196)  V.1-    1940-
   Volume(issue)/page/year: 32,1229,1971

         *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA ***

NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA :
   NOHS - National Occupational Hazard Survey (1974)
     NOHS Hazard Code - 80158
       No. of Facilities: 5059 (estimated)
       No. of Industries: 67
       No. of Occupations: 72
       No. of Employees: 55229 (estimated)
   
   NOES - National Occupational Exposure Survey (1983)
     NOES Hazard Code - 80158
       No. of Facilities: 8713 (estimated)
       No. of Industries: 100
       No. of Occupations: 82
       No. of Employees: 159582 (estimated)
       No. of Female Employees: 47852 (estimated)

                          *** STATUS IN U.S. ***
 
   EPA GENETOX PROGRAM 1988, Negative: Cell transform.-SA7/SHE
   
   EPA TSCA Section 8(b) CHEMICAL INVENTORY
   
   EPA TSCA Section 8(d) unpublished health/safety studies
   
   EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JUNE 1998

 
                            *** END OF RECORD ***