*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : BS4032000
CHEMICAL NAME           : Ammonium,
                          5-alpha-pregnan-3-beta,20-alpha-ylenebis(trimethyl-,
                          dichloride
CAS REGISTRY NUMBER     : 4795-09-9
LAST UPDATED            : 198812
DATA ITEMS CITED        : 1
MOLECULAR FORMULA       : C27-H52-N2.2Cl
MOLECULAR WEIGHT        : 475.71
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * Malouetine dichloride
   * Pregnane-3,20-diaminium, N,N,N,N',N',N'-hexamethyl-, dichloride,  
   (3-beta,5-alpha,2S)-
   * 5-alpha-Pregnan-3-beta,20-alpha-ylenebis(trimethylammonium chloride)
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 500 ug/kg
TOXIC EFFECTS :
   Peripheral Nerve and Sensation - flaccid paralysis without anesthesia
   (usually neuromuscular blockage)
   Behavioral - convulsions or effect on seizure threshold
   Lungs, Thorax, or Respiration - other changes
REFERENCE :
   APFRAD Annales Pharmaceutiques Francaises.  (SPPIF, B.P.22, F-41353 Vineuil,
   France)  V.1-    1943-  Volume(issue)/page/year: 18,678,1960
 
                            *** END OF RECORD ***