*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : BS1681000
CHEMICAL NAME           : Ammonium,
                          (p-phenylenebis(1-methylethylene))bis(trimethyl-,
                          dibromide
CAS REGISTRY NUMBER     : 10072-43-2
LAST UPDATED            : 198806
DATA ITEMS CITED        : 3
MOLECULAR FORMULA       : C18-H34-N2.2Br
MOLECULAR WEIGHT        : 438.36
WISWESSER LINE NOTATION : 1K1&1&Y1&1R D1Y1&K1&1&1 &E 2
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * p-Phenylenebis(1-methylethylene)bis(trimethylammonium bromide)
   * (p-Phenylenebis(1-methylethylene))bis(trimethylammonium) dibromide
   * Phenylene-p,p'-bis(2-trimethylammoniumpropyl) dibromide
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 75 mg/kg
TOXIC EFFECTS :
   Lungs, Thorax, or Respiration - respiratory depression
REFERENCE :
   DIPHAH Dissertationes Pharmaceuticae.  (Warsaw, Poland)  V.1-17, 1949-65.
   For publisher information, see PJPPAA.  Volume(issue)/page/year: 13,131,1961
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 10 mg/kg
TOXIC EFFECTS :
   Behavioral - convulsions or effect on seizure threshold
REFERENCE :
   AITEAT Archivum Immunologiae et Therapiae Experimentalis. (Ars Polona, POB
   1001, 00-068 Warsaw 1, Poland)  V.10-    1962-  Volume(issue)/page/year:
   14,104,1966
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 2500 ug/kg
TOXIC EFFECTS :
   Lungs, Thorax, or Respiration - respiratory depression
REFERENCE :
   DIPHAH Dissertationes Pharmaceuticae.  (Warsaw, Poland)  V.1-17, 1949-65.
   For publisher information, see PJPPAA.  Volume(issue)/page/year: 13,131,1961
 
                            *** END OF RECORD ***