*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : BS1666000
CHEMICAL NAME           : Ammonium,
                          (p-phenylenebis(1-methylethylene))bis(benzyldimethyl-
                          , dichloride
CAS REGISTRY NUMBER     : 10072-44-3
LAST UPDATED            : 198806
DATA ITEMS CITED        : 3
MOLECULAR FORMULA       : C30-H42-N2.2Cl
MOLECULAR WEIGHT        : 501.64
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * Phenylene-p,p'-bis(2-dimethylbenzylammoniumpropyl) dichloride
   * p-Phenylenebis(1-methylethylene)bis(benzyldimethylammonium chloride)
   * (p-Phenylenebis(1-methylethylene))bis(benzyldimethylammonium) dichloride
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 96 mg/kg
TOXIC EFFECTS :
   Lungs, Thorax, or Respiration - respiratory depression
REFERENCE :
   DIPHAH Dissertationes Pharmaceuticae.  (Warsaw, Poland)  V.1-17, 1949-65.
   For publisher information, see PJPPAA.  Volume(issue)/page/year: 13,131,1961
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 625 ug/kg
TOXIC EFFECTS :
   Behavioral - convulsions or effect on seizure threshold
REFERENCE :
   AITEAT Archivum Immunologiae et Therapiae Experimentalis. (Ars Polona, POB
   1001, 00-068 Warsaw 1, Poland)  V.10-    1962-  Volume(issue)/page/year:
   14,104,1966
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 525 ug/kg
TOXIC EFFECTS :
   Lungs, Thorax, or Respiration - respiratory depression
REFERENCE :
   DIPHAH Dissertationes Pharmaceuticae.  (Warsaw, Poland)  V.1-17, 1949-65.
   For publisher information, see PJPPAA.  Volume(issue)/page/year: 13,131,1961
 
                            *** END OF RECORD ***