*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : BR6450000
CHEMICAL NAME           : Ammonium,
                          (2-((imino(methylamino)methyl)thio)ethyl)triethyl-,
                          bromide, monohydrobromide
CAS REGISTRY NUMBER     : 34521-15-8
LAST UPDATED            : 199303
DATA ITEMS CITED        : 3
MOLECULAR FORMULA       : C10-H24-N3-S.Br.Br-H
MOLECULAR WEIGHT        : 379.26
WISWESSER LINE NOTATION : MUYM1&S2K2&2&2 &E &EH
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * Ethanaminium, N,N,N-triethyl-2-((imino(methylamino)methyl)thio)-,  
   bromide, monohydrobromide
   * (2-((Imino(methylamino)methyl)thio)ethyl)triethylammonium bromide  
   hydrobromide
   * N'-Methylamidinothiotriethylcholine bromide hydrobromide
   * Mteai
   * S-(2-Triethylaminoethyl)-1'-methylisothiuronium bromide hydrobromide
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 148 mg/kg
TOXIC EFFECTS :
   Behavioral - ataxia
   Lungs, Thorax, or Respiration - other changes
REFERENCE :
   CPBTAL Chemical and Pharmaceutical Bulletin.  (Japan Pub. Trading Co., USA,
   1255 Howard St., San Francisco, CA 94103)  V.6-    1958-
   Volume(issue)/page/year: 23,1639,1975
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 172 mg/kg
TOXIC EFFECTS :
   Behavioral - ataxia
   Lungs, Thorax, or Respiration - other changes
REFERENCE :
   CPBTAL Chemical and Pharmaceutical Bulletin.  (Japan Pub. Trading Co., USA,
   1255 Howard St., San Francisco, CA 94103)  V.6-    1958-
   Volume(issue)/page/year: 23,1639,1975
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 99300 ug/kg
TOXIC EFFECTS :
   Behavioral - convulsions or effect on seizure threshold
   Lungs, Thorax, or Respiration - respiratory depression
REFERENCE :
   YKKZAJ Yakugaku Zasshi.  Journal of Pharmacy.  (Nippon Yakugakkai, 2-12-15
   Shibuya, Shibuya-ku, Tokyo 150, Japan)  No.1-    1881-
   Volume(issue)/page/year: 91,1238,1971
 
                            *** END OF RECORD ***