*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : BR4550000
CHEMICAL NAME           : Ammonium, (p-hydroxyphenyl)trimethyl-, iodide,
                          methylcarbamate
CAS REGISTRY NUMBER     : 3983-40-2
LAST UPDATED            : 199112
DATA ITEMS CITED        : 3
MOLECULAR FORMULA       : C11-H17-N2-O2.I
MOLECULAR WEIGHT        : 336.20
WISWESSER LINE NOTATION : 1MVOR DK1&1&1 &Q &I
SYNONYMS/TRADE NAMES :
   * Ammonium, (4-(N-methylcarbamoyloxy)phenyl)trimethyl-, iodide
   * AR-17
   * Carbamic acid, N-methyl-, 4-dimethylaminophenyl ester, methiodide
   * Carbamic acid, N-methyl-, p-(trimethylammonio)phenyl ester, iodide
   * Methylcarbamic ester of p-oxyphenyltrimethylammonium iodide
   * Methiodide of N-methylurethane of 4-dimethylaminophenol
   * T-1088
   * TL-1097
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 50 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   JPETAB Journal of Pharmacology and Experimental Therapeutics.  (Williams &
   Wilkins Co., 428 E. Preston St., Baltimore, MD 21202)  V.1-    1909/10-
   Volume(issue)/page/year: 43,413,1931
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 50 mg/kg
TOXIC EFFECTS :
   Behavioral - coma
   Lungs, Thorax, or Respiration - respiratory stimulation
   Gastrointestinal - changes in structure or function of salivary glands
REFERENCE :
   NTIS** National Technical Information Service.  (Springfield, VA 22161)
   Formerly U.S. Clearinghouse for Scientific & Technical Information.
   Volume(issue)/page/year: PB158-508
 
TYPE OF TEST            : LD80 - Lethal Dose
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 2 mg/kg
TOXIC EFFECTS :
   Autonomic Nervous System - other (direct) parasympathomimetic
   Behavioral - coma
   Lungs, Thorax, or Respiration - respiratory stimulation
REFERENCE :
   NTIS** National Technical Information Service.  (Springfield, VA 22161)
   Formerly U.S. Clearinghouse for Scientific & Technical Information.
   Volume(issue)/page/year: PB158-508
 
                            *** END OF RECORD ***