*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : BR1600000
CHEMICAL NAME           : Ammonium, (m-hydroxyphenethyl)trimethyl-, picrate
CAS REGISTRY NUMBER     : 66967-84-8
LAST UPDATED            : 199009
DATA ITEMS CITED        : 3
MOLECULAR FORMULA       : C11-H17-N-O.C6-H3-N3-O7
MOLECULAR WEIGHT        : 408.41
WISWESSER LINE NOTATION : QR CK &WNR BO CNW ENW
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * (m-Hydroxyphenethyl)trimethylammonium picrate
   * 3-Hydroxy-N,N,N-trimethylbenzeneethanaminium picrate
   * Leptodactyline picrate
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 325 mg/kg
TOXIC EFFECTS :
   Sense Organs and Special Senses (Eye) - mydriasis (pupillary dilation)
   Sense Organs and Special Senses (Eye) - lacrimation
   Lungs, Thorax, or Respiration - other changes
REFERENCE :
   BJPCAL British Journal of Pharmacology and Chemotherapy.  (London, UK)
   V.1-33, 1946-68.  For publisher information, see BJPCBM.
   Volume(issue)/page/year: 15,14,1960
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 3300 ug/kg
TOXIC EFFECTS :
   Sense Organs and Special Senses (Eye) - mydriasis (pupillary dilation)
   Sense Organs and Special Senses (Eye) - lacrimation
   Lungs, Thorax, or Respiration - other changes
REFERENCE :
   BJPCAL British Journal of Pharmacology and Chemotherapy.  (London, UK)
   V.1-33, 1946-68.  For publisher information, see BJPCBM.
   Volume(issue)/page/year: 15,14,1960
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Bird - pigeon
DOSE/DURATION           : 120 ug/kg
TOXIC EFFECTS :
   Sense Organs and Special Senses (Eye) - mydriasis (pupillary dilation)
   Behavioral - convulsions or effect on seizure threshold
   Gastrointestinal - other changes
REFERENCE :
   BJPCAL British Journal of Pharmacology and Chemotherapy.  (London, UK)
   V.1-33, 1946-68.  For publisher information, see BJPCBM.
   Volume(issue)/page/year: 15,14,1960
 
                            *** END OF RECORD ***