*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : AC3900000
CHEMICAL NAME           : Acetamide, N-hydroxy-N-1-pyrenyl-
CAS REGISTRY NUMBER     : 95331-48-9
LAST UPDATED            : 199410
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C18-H13-N-O2
MOLECULAR WEIGHT        : 275.32
COMPOUND DESCRIPTOR     : Tumorigen
                          Mutagen
SYNONYMS/TRADE NAMES :
   * N-Hydroxy-N-acetyl-1-aminopyrene
   * N-Hydroxy-N-1-pyrenylacetamide
 
                       *** HEALTH HAZARD DATA ***
 
                          ** TUMORIGENIC DATA **
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 164 mg/kg/4W-I
TOXIC EFFECTS :
   Tumorigenic - equivocal tumorigenic agent by RTECS criteria
   Skin and Appendages - tumors
REFERENCE :
   CNREA8 Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut
   Sts., Philadelphia, PA 19106)  V.1-    1941-  Volume(issue)/page/year:
   51,2902,1991
 
                            ** MUTATION DATA **
 
TYPE OF TEST            : Mutation in microorganisms
TEST SYSTEM             : Bacteria - Salmonella typhimurium
DOSE/DURATION           : 1 ug/plate
REFERENCE :
   MUREAV Mutation Research.  (Elsevier Science Pub. B.V., POB 211, 1000 AE
   Amsterdam, Netherlands) V.1-    1964-  Volume(issue)/page/year: 138,113,1984
 
                            *** END OF RECORD ***