*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : AB7420000
CHEMICAL NAME           : Acetamide,
                          N,N-diethyl-N'-(1,2,3,4-tetrahydro-1-naphthyl)-
LAST UPDATED            : 198910
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C16-H24-N2-O
MOLECULAR WEIGHT        : 260.42
WISWESSER LINE NOTATION : L66&TJ GM1VN2&2
COMPOUND DESCRIPTOR     : Drug
                          Reproductive Effector
SYNONYMS/TRADE NAMES :
   * N,N-Diethyl-N'-(1,2,3,4-tetrahydro-1-naphthyl)acetamide
   * N,N-Diethyl-N'-2-(tetrahydro-1,2,3,4-naphthyl)-glycinamide
   * N,N-Diethyl-N'-2-(tetralyl)-glycinamide
   * 621 I.S.
   * Tochergamine
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - rabbit
DOSE/DURATION           : 40 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans
   Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium)  V.4-   
   1898-  Volume(issue)/page/year: 96,327,1954
 
                          ** REPRODUCTIVE DATA **
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Intramuscular
SPECIES OBSERVED        : Rodent - rat
DOSE                    : 100 mg/kg
SEX/DURATION            : female 5 day(s) after conception
TOXIC EFFECTS :
   Reproductive - Fertility - pre-implantation mortality (e.g. reduction in
   number of implants per female; total number of implants per corpora lutea)
   Reproductive - Effects on Newborn - stillbirth
REFERENCE :
   PSEBAA Proceedings of the Society for Experimental Biology and Medicine.
   (Academic Press, Inc., 1 E. First St., Duluth, MN 55802)  V.1-    1903/04-
   Volume(issue)/page/year: 100,555,1959
 
                            *** END OF RECORD ***