*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : AB6353000
CHEMICAL NAME           : Acetamide,
                          2-(dibutylamino)-N-(2,5-dimethylpyrrol-1-yl)-
CAS REGISTRY NUMBER     : 20627-22-9
BEILSTEIN REFERENCE NO. : 1686689
LAST UPDATED            : 199612
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C16-H29-N3-O
MOLECULAR WEIGHT        : 279.48
WISWESSER LINE NOTATION : T5NTJ AMV1N4&4 B1 E1
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * 2-(Dibutylamino)-N-(2,5-dimethylpyrrol-1-yl)acetamide
   * R 459
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 1100 mg/kg
TOXIC EFFECTS :
   Behavioral - tremor
   Behavioral - changes in psychophysiological tests
   Lungs, Thorax, or Respiration - dyspnea
REFERENCE :
   CHTPBA Chimica Therapeutica.  (Paris, France)  V.1-8, 1965-73.  For
   publisher information, see EJMCA5.  Volume(issue)/page/year: 3,445,1968
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 22 mg/kg
TOXIC EFFECTS :
   Behavioral - tremor
   Behavioral - changes in psychophysiological tests
   Lungs, Thorax, or Respiration - dyspnea
REFERENCE :
   CHTPBA Chimica Therapeutica.  (Paris, France)  V.1-8, 1965-73.  For
   publisher information, see EJMCA5.  Volume(issue)/page/year: 3,445,1968
 
                            *** END OF RECORD ***