*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : AB5836500
CHEMICAL NAME           : Acetamide,
                          2-((6-chloro-3-pyridazinyl)thio)-N,N-diethyl-
CAS REGISTRY NUMBER     : 1830-32-6
BEILSTEIN REFERENCE NO. : 0885011
REFERENCE               : 5-23-11-00092 (Beilstein Handbook Reference)
LAST UPDATED            : 199612
DATA ITEMS CITED        : 4
MOLECULAR FORMULA       : C10-H14-Cl-N3-O-S
MOLECULAR WEIGHT        : 259.78
WISWESSER LINE NOTATION : T6NNJ CG FS1VN2&2
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * Azintamide
   * Azinthiamide
   * Bilipurum
   * Biloral
   * (3-Chloro-pyridazinyl-(6)-thio)-acetic acid diethylamide
   * 2-((6-Chloro-3-pyridazinyl)thio)-N,N-diethylacetamide
   * (3-Chlor-pyridazinyl-(6)-thio)-essigsaeurediaethylamid
   * Colerin
   * N,N-Diethyl-2-(6-(3-chloropyridazinyl)mercapto)acetamide
   * N,N-Diethyl-2-(6-(3-chloropyridazinyl)thio)acetamide
   * Oragal
   * Oragalin
   * Oragallin
   * Oragallin purum
   * ST 9067
   * X 23
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 1550 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   ARZNAD Arzneimittel-Forschung. Drug Research.  (Editio Cantor Verlag,
   Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.)  V.1-    1951-
   Volume(issue)/page/year: 14,266,1964
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 540 mg/kg
TOXIC EFFECTS :
   Behavioral - convulsions or effect on seizure threshold
   Behavioral - ataxia
   Lungs, Thorax, or Respiration - dyspnea
REFERENCE :
   ARZNAD Arzneimittel-Forschung. Drug Research.  (Editio Cantor Verlag,
   Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.)  V.1-    1951-
   Volume(issue)/page/year: 24,111,1974
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 1150 mg/kg
TOXIC EFFECTS :
   Behavioral - convulsions or effect on seizure threshold
   Behavioral - ataxia
   Lungs, Thorax, or Respiration - dyspnea
REFERENCE :
   ARZNAD Arzneimittel-Forschung. Drug Research.  (Editio Cantor Verlag,
   Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.)  V.1-    1951-
   Volume(issue)/page/year: 24,111,1974
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 700 mg/kg
TOXIC EFFECTS :
   Behavioral - convulsions or effect on seizure threshold
   Behavioral - ataxia
   Lungs, Thorax, or Respiration - dyspnea
REFERENCE :
   ARZNAD Arzneimittel-Forschung. Drug Research.  (Editio Cantor Verlag,
   Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.)  V.1-    1951-
   Volume(issue)/page/year: 24,111,1974
 
                            *** END OF RECORD ***