*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : AB5798000
CHEMICAL NAME           : Acetamide,
                          N-(4-chloro-6-(4-methyl-1-piperazinyl)-5-(methylthio)
                          -2-pyrimidinyl)-N-met hyl-, monohydrochloride
CAS REGISTRY NUMBER     : 55477-39-9
LAST UPDATED            : 199703
DATA ITEMS CITED        : 1
MOLECULAR FORMULA       : C13-H20-Cl-N5-O-S.Cl-H
MOLECULAR WEIGHT        : 366.35
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   *   2-(N-Methyl-N-acetyl)amino-4-N-methylpiperazino-5-methylthio-6-chloro-py
     rimidine hydrochloride
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 525 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   JMCMAR Journal of Medicinal Chemistry.  (American Chemical Soc.,
   Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC
   20037)  V.6-    1963-  Volume(issue)/page/year: 18,553,1975
 
                            *** END OF RECORD ***