【药物名称】Mitozantrone hydrochloride, Mitoxantrone hydrochloride, DAD, NSC-301739, CL-232315, Onkotrone, Novantrone, Novantron
化学结构式(Chemical Structure):
参考文献No.201789
标题:CL-232315
作者:Blancafort, P.; Sweetman, A.J.; Casta馿r, J.; Serradell, M.N.
来源:Drugs Fut 1980,5(5),234
合成路线图解说明:

By reaction of 5,8-dihydroxyleucoquinizarin (1,4,5,8-tetrahydroxy-9,10-anthraquinone) (I) with 2-(aminoethylamino)ethanol (II) in dioxane at 60 C.

参考文献No.607181
标题:Antineoplastic agents. Structure-activity relationship study of bis(substituted aminoalkylamino)anthraquinones
作者:Zee-Cheng, R.K.Y.; Cheng, C.C.
来源:J Med Chem 1978,21(3),291-294
合成路线图解说明:

By reaction of 5,8-dihydroxyleucoquinizarin (1,4,5,8-tetrahydroxy-9,10-anthraquinone) (I) with 2-(aminoethylamino)ethanol (II) in dioxane at 60 C.

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