【药物名称】Norfloxacin, MK-0366, AM-715, Norflo, Lexinor, Baccidal, Sebercim, Noroxin, Fulgram, Barazan
化学结构式(Chemical Structure):
参考文献No.47502
标题:Piperazinyl derivs. of quinoline carboxylic acids
作者:Irikura, T. (Kyorin Pharmaceutical Co., Ltd.)
来源:US 4146719
合成路线图解说明:

By condensation of 1-ethyl-6-fluoro-7-chloro-1,4-dihydro-4-oxo-3-quinolinecarboxylic acid (I) with piperazine (II) by heating at 170 C in water in a pressure tube.

参考文献No.800455
标题:AM-715
作者:Blancafort, P.; Sweetman, A.J.; Casta馿r, J.; Serradell, M.N.
来源:Drugs Fut 1981,6(8),462
合成路线图解说明:

By condensation of 1-ethyl-6-fluoro-7-chloro-1,4-dihydro-4-oxo-3-quinolinecarboxylic acid (I) with piperazine (II) by heating at 170 C in water in a pressure tube.

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