Azelaic acid, ZK-62498, AGN-191861, SH-441, Finacea, Finevin, Azelex, Skinoren, Skinorem-药物合成数据库

【药物名称】Azelaic acid, ZK-62498, AGN-191861, SH-441, Finacea, Finevin, Azelex, Skinoren, Skinorem

化学结构式(Chemical Structure):

参考文献No.	66953
标题:	Azelaic Acid
作者:	Casta馿r, J.; Passi, S.; Serradell, M.N.; Picardo, M.; Porro, M.N.; Blancafort, P.
来源:	Drugs Fut 1983,8(1),9

合成路线图解说明: The hydrolysis of glycerol ricinoleate (castor oil) (I) with KOH in refluxing 95% ethanol gives ricinoleic acid (II), which is oxidized with KMnO4 in water with KOH.

参考文献No.	84652
标题:	Azelaic acid
作者:	Hill, J.W.; McEwen, W.L.
来源:	Org Synth Coll 1943,II53-55

合成路线图解说明: The hydrolysis of glycerol ricinoleate (castor oil) (I) with KOH in refluxing 95% ethanol gives ricinoleic acid (II), which is oxidized with KMnO4 in water with KOH.