Glunicate, LG-13979-药物合成数据库

【药物名称】Glunicate, LG-13979

化学结构式(Chemical Structure):

参考文献No.	75187
标题:	Glunicate
作者:	Subissi, A.
来源:	Drugs Fut 1984,9(12),898

合成路线图解说明: Reaction of D-(+)-glucosamine HCl, with six equivalents of 3-pyridinylcarbonyl chloride (III) in hot pyridine gives a mixture of alpha and beta-penta-substituted D-(+)-glucosamines and lower substituted D-(+)-glucosamines, from which compound (III) is isolated by crystallization.

参考文献No.	701187
标题:	Nicotinic derivatives of glucosamine and related pharmaceutical compositions
作者:	Murmann, W.; Ponchiroli, O.
来源:	EP 0040433; ES 8203362; FR 2482968; US 4358441

合成路线图解说明: Reaction of D-(+)-glucosamine HCl, with six equivalents of 3-pyridinylcarbonyl chloride (III) in hot pyridine gives a mixture of alpha and beta-penta-substituted D-(+)-glucosamines and lower substituted D-(+)-glucosamines, from which compound (III) is isolated by crystallization.