Nafamostat mesilate, Nafamostat mesylate, FUT-175, Futhan-药物合成数据库

【药物名称】Nafamostat mesilate, Nafamostat mesylate, FUT-175, Futhan

化学结构式(Chemical Structure):

参考文献No.	46051
标题:	Amidine compound
作者:	Fujii, S.; Okutome, T.; Nakayama, T.; Yaegashi, T.; Kurumi, M. (Torii Pharmaceutical Co., Ltd.)
来源:	JP 82179146; JP 8253454; US 4454338

合成路线图解说明: This compound can be prepared by condensation of 4-guanidinobenzoic acid (I) with 6-amidino-2-naphthol (II) in pyridine either by means of DCC or the acid chloride of (I), (III), at room temperature.

参考文献No.	61930
标题:	Nafamstat Mesylate
作者:	Aoyama, T.
来源:	Drugs Fut 1984,9(10),747

合成路线图解说明: This compound can be prepared by condensation of 4-guanidinobenzoic acid (I) with 6-amidino-2-naphthol (II) in pyridine either by means of DCC or the acid chloride of (I), (III), at room temperature.