【药物名称】CGP-15720A
化学结构式(Chemical Structure):
参考文献No.42030
标题:Imidazole urea and amino compounds
作者:Marxer, A. (Novartis Corp.)
来源:EP 0004561; GB 2016011; JP 79125668; SA 7901062; US 4292429
合成路线图解说明:

The condensation of 1-(2-aminoethyt)-2-(4 pyridyl)-2-imidazoline (I) with 4-(ethoxycarbonyl)phenyi isocyanate (II) gives the corresponding urea (III), which is hydrolyzed with NaOH in 95% ethanol.

参考文献No.70121
标题:CGP-15720 A
作者:Prous, J.; Casta馿r, J.
来源:Drugs Fut 1986,11(8),641
合成路线图解说明:

The condensation of 1-(2-aminoethyt)-2-(4 pyridyl)-2-imidazoline (I) with 4-(ethoxycarbonyl)phenyi isocyanate (II) gives the corresponding urea (III), which is hydrolyzed with NaOH in 95% ethanol.

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