【药物名称】Pirfenidone, S-7701, AMR-69, Deskar
化学结构式(Chemical Structure):
参考文献No.67239
标题:Pirfenidone
作者:Casta馿r, J.; Blancafort, P.
来源:Drugs Fut 1977,2(6),396
合成路线图解说明:

By condensation of 5-methyl-2-(1H)-pyridone (I) with iodobenzene (II) by means of K2CO3 and Copper powder at reflux temperature.

参考文献No.701092
标题:N-Substituted pyridone and general method for preparing pyridones
作者:Gadekar, S.M.
来源:US 3839346; ZA 7309472
合成路线图解说明:

By condensation of 5-methyl-2-(1H)-pyridone (I) with iodobenzene (II) by means of K2CO3 and Copper powder at reflux temperature.

参考文献No.701093
标题:5-Methyl-1-phenyl-2-(1H)-pyridone compositions and methods of use
作者:Gadekar, S.M.
来源:CA 1049411; DE 2555411; US 3974281
合成路线图解说明:

By condensation of 5-methyl-2-(1H)-pyridone (I) with iodobenzene (II) by means of K2CO3 and Copper powder at reflux temperature.

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