Triglycidylurazol, Anaxirone, NSC-332488, TGU-药物合成数据库

【药物名称】Triglycidylurazol, Anaxirone, NSC-332488, TGU

化学结构式(Chemical Structure):

参考文献No.	46478
标题:	N-Substituted polyglycidyl urazole compounds, processes for their production and pharmaceutical preparations
作者:	Fischer, H.; et al. (Henkel KgA)
来源:	EP 0056962; JP 57142982; US 4801601

合成路线图解说明: For synthesizing alpha/beta-TGU a mixture of urazole (I), epichlorohydrin (II) and tetramethylammonium bromide or benzalcon A was heated to yield the corresponding chlorohydrin intermediate (III), which was converted to alpha/beta-TGU by addition of sodium hydroxide and purified by column chromatography or recrystallization.

参考文献No.	63554
标题:	Triglycidylurazol
作者:	Casta馿r, J.; Serradell, M.N.
来源:	Drugs Fut 1984,9(3),209

合成路线图解说明: For synthesizing alpha/beta-TGU a mixture of urazole (I), epichlorohydrin (II) and tetramethylammonium bromide or benzalcon A was heated to yield the corresponding chlorohydrin intermediate (III), which was converted to alpha/beta-TGU by addition of sodium hydroxide and purified by column chromatography or recrystallization.