【药物名称】Disoprofol, Propofol, AM-149(New formulation), ZD-0859, ICI-35868, Ampofol, Propofol IDD-D, Disoprivan, Diprivan
化学结构式(Chemical Structure):
参考文献No.49289
标题:Disoprofol
作者:Serradell, M.N.; Casta馿r, J.; Sneddon, J.M.; Blancafort, P.
来源:Drugs Fut 1982,7(3),156
合成路线图解说明:

By condensation of phenol (I) with propylene (II) at temperatures ranging from 230 C to 275 C and pressures up to 3000 atm. in an autoclave, using aluminum phenoxide as catalyst.

参考文献No.800191
标题:The ortho-alkylation of phenols
作者:Napolitano, J.P.; Ecke, G.G.; Kolka, A.J.
来源:J Org Chem 1956,21712-713
合成路线图解说明:

By condensation of phenol (I) with propylene (II) at temperatures ranging from 230 C to 275 C and pressures up to 3000 atm. in an autoclave, using aluminum phenoxide as catalyst.

参考文献No.800192
标题:The ortho-alkylation of phenols
作者:Ecke, G.G.; Kolka, A.J.; Napolitano, J.P.; Filbey, A.H.
来源:J Org Chem 1957,22642-646
合成路线图解说明:

By condensation of phenol (I) with propylene (II) at temperatures ranging from 230 C to 275 C and pressures up to 3000 atm. in an autoclave, using aluminum phenoxide as catalyst.

参考文献No.800193
标题:Thermal addition reactions of monocyclic phenols with ethylene
作者:Kealy, T.J.; Coffman, D.D.
来源:J Org Chem 1961,26987-992
合成路线图解说明:

By condensation of phenol (I) with propylene (II) at temperatures ranging from 230 C to 275 C and pressures up to 3000 atm. in an autoclave, using aluminum phenoxide as catalyst.

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