Naflocort, SQ-26490-药物合成数据库

【药物名称】Naflocort, SQ-26490

化学结构式(Chemical Structure):

参考文献No.	45874
标题:	Steroidal[16alpha,17beta]naphtalenes
作者:	Varma, R.K.; Cimarusti, C.M. (Bristol-Myers Squibb Co.)
来源:	DE 2551562; FR 2291762; GB 1512400; JP 51076258; JP 61063693; US 3937720

合成路线图解说明: By condensation of 9-fluoro-11-beta-21-dihydroxypregna-1,4,16-triene-3,20-dione (I) with benzocyclobutene (II) at reflux temperature in nitrogen atmosphere.

参考文献No.	63055
标题:	Naflocort
作者:	Pento, J.T.; Serradell, M.N.; Casta馿r, J.
来源:	Drugs Fut 1986,11(2),110

合成路线图解说明: By condensation of 9-fluoro-11-beta-21-dihydroxypregna-1,4,16-triene-3,20-dione (I) with benzocyclobutene (II) at reflux temperature in nitrogen atmosphere.