-药物合成数据库

【药物名称】

化学结构式(Chemical Structure):

参考文献No.	51586
标题:	Pyrrole-2,5-dione derivs. for the treatment of diabetes
作者:	Smith, D.G.; Haigh, D.; Ward, R.W.; Slingsby, B.P. (GlaxoSmithKline plc)
来源:	WO 0174771

合成路线图解说明: The condensation of 3-chloro-4-(2,3-difluorophenyl)-2,5-dihydro-1H-pyrrole-2,5-dione (I) with 5-amino-2,3-dihydrobenzothiazol-2-one (II) by means of TEA in refluxing methanol gives the target secondary amine.