PQ-药物合成数据库

【药物名称】PQ

化学结构式(Chemical Structure):

参考文献No.	666874
标题:	Inhibition of leukocyte functions by the alkaloid isaindigotone from Isatis indigotica and some new synthetic derivatives
作者:	Molina, P.; Tarraga, A.; Gonzalez-Tejero, A.; Rioja, I.; Ubeda, A.; Terencio, M.C.; Alcaraz, M.J.
来源:	J Nat Prod 2001,64(10),1297

合成路线图解说明: Deoxyvascinone (III) is prepared from o-azidobenzoyl chloride (I) and 2-pyrrolidinone (II) following a reported procedure. Then, Claisen-Schmidt condensation between deoxyvascinone (III) and 4-acetoxy-3,5-dimethoxybenzaldehyde (IV) in boiling acetic anhydride leads to the title compound.