LM-1685-药物合成数据库

【药物名称】LM-1685

化学结构式(Chemical Structure):

参考文献No.	659983
标题:	Identification of novel cyclooxygenase-2 selective inhibitors using pharmacophore models
作者:	Palomer, A.; Cabr? F.; Pascual, J.; Campos, J.; Trujillo, M.A.; Entrena, A.; Gallo, M.A.; Garc韆, L.; Maule髇, D.; Espinosa, A.
来源:	J Med Chem 2002,45(7),1402

合成路线图解说明: The title compound was obtained by the alkylation of methyl 5-(methylsulfonyl)indole-2-carboxylate (I) with 4-chlorobenzyl bromide (II) in the presence of KOH.