【药物名称】
化学结构式(Chemical Structure):
参考文献No.646714
标题:Synthesis and antibacterial activity of novel piperazinyl-linked fluoroquinolones
作者:Grucz, R.G.; Kerns, R.J.; Kaatz, G.W.; Vaka, F.; Rybak, M.J.
来源:41st Intersci Conf Antimicrob Agents Chemother (Dec 16 2001, Chicago) 2001,Abst F-565
合成路线图解说明:

The alkylation of ciprofloxacin (I) with bis(chloromethyl)benzene (II) afforded the monosubstituted adduct (III). This was further condensed with norfloxacin (IV) to yield the title heterodimer compound.

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