Droxicainide, S-1249, AL-S-1249-药物合成数据库

【药物名称】Droxicainide, S-1249, AL-S-1249

化学结构式(Chemical Structure):

参考文献No.	804003
标题:	Droxicainide
作者:	Aberg, G.
来源:	Drugs Fut 1983,8(6),492

合成路线图解说明: A pyridine carboxylic acid anilide (III) can be produced by reacting a pyridine carboxylic acid chloride (I) with an aromatic amine (II). The pyridine carboxylic acid anilide (III) is hydrogenated to the corresponding piperidine carboxylic acid anilide (IV), which is thereafter hydroalkylated

参考文献No.	900232
标题:
作者:	af Ekenstam, B.; Aberg, A.K.G.
来源:	US 4302465

合成路线图解说明: A pyridine carboxylic acid anilide (III) can be produced by reacting a pyridine carboxylic acid chloride (I) with an aromatic amine (II). The pyridine carboxylic acid anilide (III) is hydrogenated to the corresponding piperidine carboxylic acid anilide (IV), which is thereafter hydroalkylated