Broperamole, TR-2378-药物合成数据库

【药物名称】Broperamole, TR-2378

化学结构式(Chemical Structure):

参考文献No.	804007
标题:	Broperamole
作者:	Blancafort, P.; Serradell, M.N.; Casta馿r, J.; Arrigoni, Martelli, E.
来源:	Drugs Fut 1981,6(4),214

合成路线图解说明: The chlorination of 3-[5-(m-bromophenyl)-2H-tetrazol-2-yl]propionic acid (I) with thionyl chloride in refluxing chloroform gives the corresponding acyl chloride (II), which is then treated with dry piperidine (III) in THF

参考文献No.	900235
标题:
作者:
来源:	CA 950908; DE 2063173; FR 2081397; GB 1319357; GB 1320140; JP 7141904; US 3681336

合成路线图解说明: The chlorination of 3-[5-(m-bromophenyl)-2H-tetrazol-2-yl]propionic acid (I) with thionyl chloride in refluxing chloroform gives the corresponding acyl chloride (II), which is then treated with dry piperidine (III) in THF