Amantinium bromide-药物合成数据库

【药物名称】Amantinium bromide

化学结构式(Chemical Structure):

参考文献No.	900298
标题:
作者:	Rovati, L.; Makovec, F.; Senin, P.
来源:	BE 860980; DE 2752318; FR 2373514; GB 1574536; JP 65864; JP 8237582; US 4288609

合成路线图解说明: This compound can be obtained as follows: The comdensation of 1-adamantanecarboxylic acid (I) with 2-(dimethylamino)ethanol (II) by means of dicyclohexylcarbodiimide (DCC) gives 2-(dimethylamino)ethyl 1-adamantanecarboxylate (III), which is then quaternized with decyl bromide (IV).

参考文献No.	950039
标题:	Amantanium Bromide
作者:	Serradell, M.N.; Casta馿r, J.
来源:	Drugs Fut 1984,9(3),167

合成路线图解说明: This compound can be obtained as follows: The comdensation of 1-adamantanecarboxylic acid (I) with 2-(dimethylamino)ethanol (II) by means of dicyclohexylcarbodiimide (DCC) gives 2-(dimethylamino)ethyl 1-adamantanecarboxylate (III), which is then quaternized with decyl bromide (IV).