【药物名称】
化学结构式(Chemical Structure):
参考文献No.30890
标题:Further indole derivs. with antiviral activity
作者:Slater, M.J.; Cockerill, G.S.; Littler, E.; Yeates, C.L. (Glaxo Wellcome plc)
来源:US 5547976; WO 9318766
合成路线图解说明:

The known indolopyrrolocarbazole (I) was protected as the bis-Boc derivative (II) upon treatment with Boc2O and NaH in DMF. Alkylation of (II) with ethyl iodide in the presence of NaH furnished the mono-ethyl compound (III), which was finally deprotected by means of HCl in EtOAc.

参考文献No.629295
标题:Synthesis of N-alkyl substituted indolocarbazoles as potent inhibitors of human cytomegalovirus replication
作者:Slater, M.J.; Baxter, R.; Bonser, R.W.; Cockerill, S.; Gohil, K.; Parry, N.; Robinson, E.M.; Randall, R.; Yeates, C.; Snowden, W.; Walters, A.
来源:Bioorg Med Chem Lett 2001,11(15),1993
合成路线图解说明:

The known indolopyrrolocarbazole (I) was protected as the bis-Boc derivative (II) upon treatment with Boc2O and NaH in DMF. Alkylation of (II) with ethyl iodide in the presence of NaH furnished the mono-ethyl compound (III), which was finally deprotected by means of HCl in EtOAc.

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