-药物合成数据库

【药物名称】

化学结构式(Chemical Structure):

参考文献No.	610527
标题:	Telomerase inhibitors based on quadruplex ligands selected by a fluorescence assay
作者:	Mergny, J.-L.; Lacroix, L.; Teulade-Frchou, M.-P.; Hounsou, C.; Guittat, L.; Hoarau, M.; Arimondo, P.B.; Vigneron, J.P.; Lehn, J.M.; Riou, J.F.; Garestier, T.; Helene, C.
来源:	Proc Natl Acad Sci USA 2001,98(6),3062

合成路线图解说明: The title compound was prepared starting from dibenzo[b,j](1,7)phenanthroline-2,10-dicarboxaldehyde (I). Condensation of dialdehyde (I) with 3-(dimethylamino)propylamine (II) produced the intermediate diimine (III), which was then reduced to the corresponding amine by using NaBH4 in MeOH.