【药物名称】
化学结构式(Chemical Structure):
参考文献No.55235
标题:Aromatic and heterocyclic thiazolyl thiourea cpds. and use
作者:Uckun, F.M.; Venkatachalam, T.K. (Parker Hughes Institute)
来源:WO 0232889
合成路线图解说明:

Reaction of 2-aminothiazole (I) with thiocarbonyldiimidazole (II) in acetonitrile gave the intermediate thioimidazolide (III). This was then condensed with 2-furylmethylamine (IV) in hot DMF to yield the title thiourea derivative.

参考文献No.609857
标题:Anti-HIV activity of aromatic and heterocyclic thiazolyl thiourea compounds
作者:Venkatachalam, T.K.; Sudbeck, E.A.; Mao, C.; Uckun, F.M.
来源:Bioorg Med Chem Lett 2001,11(4),523
合成路线图解说明:

Reaction of 2-aminothiazole (I) with thiocarbonyldiimidazole (II) in acetonitrile gave the intermediate thioimidazolide (III). This was then condensed with 2-furylmethylamine (IV) in hot DMF to yield the title thiourea derivative.

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