【药物名称】Mibolerone
化学结构式(Chemical Structure):
参考文献No.612823
标题:Mibolerone
作者:Casta馿r, J.; Bogan, J.A.
来源:Drugs Fut 1976,1(5),247
合成路线图解说明:

By direct methylation of 7alpha-methyl-19-nor-4-androsten-3,17-dione 3-pyrrolidyl enamine (I) with methylmagnesium bromide in THF, followed by hydrolysis of the enamine group with base.

参考文献No.900293
标题:
作者:Babcock, J.C.; Campbell, A.
来源:US 3341557
合成路线图解说明:

By direct methylation of 7alpha-methyl-19-nor-4-androsten-3,17-dione 3-pyrrolidyl enamine (I) with methylmagnesium bromide in THF, followed by hydrolysis of the enamine group with base.

参考文献No.900294
标题:
作者:
来源:NL 6604702
合成路线图解说明:

By direct methylation of 7alpha-methyl-19-nor-4-androsten-3,17-dione 3-pyrrolidyl enamine (I) with methylmagnesium bromide in THF, followed by hydrolysis of the enamine group with base.

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