AWD-33-159-药物合成数据库

【药物名称】AWD-33-159

化学结构式(Chemical Structure):

参考文献No.	42235
标题:	New 4-amino-1-aryl-pyridine-2-ones with anticonvulsive action and method for producing same
作者:	Bartsch, R.; Rostock, A.; Lankau, H.-J.; Unverferth, K.; Arnold, T.; Granik, V.; Grizik, S. (AWD.pharma GmbH & Co. KG)
来源:	DE 19835918; EP 1102748; JP 2002522420; WO 0007988

合成路线图解说明: The title N-phenylpyrimidinone was prepared from the previously reported pyrimidine cyano ester (I) by alkaline hydrolysis with 10% NaOH followed by heating at 180 C in 75% H2SO4..