-药物合成数据库

【药物名称】

化学结构式(Chemical Structure):

参考文献No.	567500
标题:	The cyclohexene ring system as a furanose mimic: Synthesis and antiviral activity of both enantiomers of cyclohexenylguanine
作者:	Wang, J.; Froeyen, M.; Hendrix, C.; Andrei, G.; Snoeck, R.; De Clercq, E.; Herdewijn, P.
来源:	J Med Chem 2000,43(4),736

合成路线图解说明: Coupling of known allylic alcohol (I) with 2-amino-6-chloropurine (II) under Mitsunobu conditions furnished nucleoside (III). Subsequent desilylation and chloride hydrolysis by means of aqueous trifluoroacetic acid yielded the title compound.