-药物合成数据库

【药物名称】

化学结构式(Chemical Structure):

参考文献No.	563831
标题:	Synthesis and in vitro anti-Mycobacterium activity of N-alkyl-1,2-dihydro-2-thioxo-3-pyridinecarbothioamides. Preliminary toxicity and pharmacokinetic evaluation
作者:	Pagani, G.; Pregnolato, M.; Ubiali, D.; Terreni, M.; Piersimoni, C.; Scaglione, F.; Fraschini, F.; Gascon, A.R.; Pedraz, Munoz .J.L.
来源:	J Med Chem 2000,43(2),199

合成路线图解说明: The target compound can be obtained by treatment of 3H-1,2-dithiolo[3,4-b]pyridine-3-thione (I) with ethylamine (II) in refluxing EtOH.