Coupling of dihydroartemisinin (I) with allyl trimethylsilane in the presence of boron trifluoride etherate gave the 10beta-allyl deoxo derivative (II). Subsequent ozonization of the allyl double bond of (II), followed by reductive treatment with NaBH4, provided alcohol (III). Finally, alkylation of (III) with 2-fluorobenzyl bromide (IV) in the presence of NaH furnished the corresponding 2-fluorobenzyl ether.