-药物合成数据库

【药物名称】

化学结构式(Chemical Structure):

参考文献No.	552007
标题:	Imidazole substituted biphenyls: A new class of highly potent and in vivo active inhibitors of P450 17 as potential therapeutics for treatment of prostate cancer
作者:	Wachall, B.G.; Hector, M.; Zhuang, Y.; Hartmann, R.W.
来源:	Bioorg Med Chem 1999,7(9),1913

合成路线图解说明: This compound has been obtained by condensation of 1-(4-bromobenzyl)imidazole (I) with 4-fluorophenylboronic acid (II) by means of Pd(PPh3)4 and Na2CO3 in refluxing toluene/ethanol.