-药物合成数据库

【药物名称】

化学结构式(Chemical Structure):

参考文献No.	43329
标题:	Cyclohexamide derivs. which influence the regeneration of neural tissue
作者:	Thiericke, R.; Fischer, G.; K黮lertz, G.; Christner, C.; Grabley, S.; Wyrwa, R. (Hans Kn鰈l Institute for Natural Product Research; Max-Planck-Gesellschaft zur F鰎derung der Wissenschaften e.V. )
来源:	WO 0026188

合成路线图解说明: By condensation of cycloheximide (I) with ethyl 2-bromoacetate (II) by means of K2CO3 and 18-crown-6 in acetone.

参考文献No.	548634
标题:	Synthesis and cytotoxic evaluation of cycloheximide derivatives as potential inhibitors of FKBP12 with neuroregenerative properties
作者:	Christner, C.; Wyrwa, R.; Marsch, S.; K黮lertz, G.; Thiericke, R.; Grabley, S.; Schummann, D.; Fischer, G.
来源:	J Med Chem 1999,42(18),3615

合成路线图解说明: By condensation of cycloheximide (I) with ethyl 2-bromoacetate (II) by means of K2CO3 and 18-crown-6 in acetone.