The previously reported chiral cyclopentanedicarboxylic acid monoester (I) was converted to the mixed anhydride (II) by treatment with ethyl chloroformate in the presence of triethylamine. Reduction of the mixed anhydride (II) with NaBH4 in cold MeOH produced the corresponding alcohol, which, under the reaction conditions, gave rise to the bicyclic lactone (III). Then, the lithium enolate generated from lactone (III) and lithium hexamethyldisilazide was alkylated with 2-(bromomethyl)naphthalene (IV) to produce the title compound.