【药物名称】
化学结构式(Chemical Structure):
参考文献No.566132
标题:1,3-Diarylcycloalkano-[1,2-d]-pyrazoles and diphenyl hydrazides as selective inhibitors of cyclooxygenase-2
作者:Sui, Z.; et al.
来源:217th ACS Natl Meet (March 21 1999, Anaheim) 1999,Abst MEDI 202
合成路线图解说明:

The title hydrazide was prepared from 4-chlorobenzoic acid (I) via conversion to the corresponding acid chloride (II), followed by condensation with 4-methylphenylhydrazine (III).

参考文献No.576834
标题:1,3-Diarylcycloalkanopyrazoles and diphenyl hydrazides as selective inhibitors of cyclooxygenase-2
作者:Sui, Z.; Guan, J.; Ferro, M.P.; McCoy, K.; Wachter, M.P.; Murray, W.V.; Singer, M.; Steber, M.; Ritchie, D.M.; Argentieri, D.C.
来源:Bioorg Med Chem Lett 2000,10(6),601
合成路线图解说明:

The title hydrazide was prepared from 4-chlorobenzoic acid (I) via conversion to the corresponding acid chloride (II), followed by condensation with 4-methylphenylhydrazine (III).

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