-药物合成数据库

【药物名称】

化学结构式(Chemical Structure):

参考文献No.	530552
标题:	Antimalarial activity of 3-hydroxyalkyl-2-methylene-propionic acid derivatives
作者:	Kundu, M.K.; Sundar, N.; Kumar, S.K.; Bhat, S.V.; Biswas, S.; Valecha, N.
来源:	Bioorg Med Chem Lett 1999,9(5),731

合成路线图解说明: The title compound was synthesized through Baylis-Hillman reaction of p-nitrobenzaldehyde (I) with acrylonitrile (II) in the presence of 1,4-diazabicyclo[2.2.2]octane (DABCO) and NaI.