BM2419-1-药物合成数据库

【药物名称】BM2419-1

化学结构式(Chemical Structure):

参考文献No.	482619
标题:	Novel selective inhibitors for human topoisomerase I, BM2419-1 and -2 derived from saintopin
作者:	Ishiyama, D.; Futamata, K.; Futamata, M.; Kasuya, O.; Kamo, S.; Yamashita, F.; Kanazawa, S.
来源:	J Antibiot 1998,51(12),1069

合成路线图解说明: Title compound was generated during the extraction of saintopin (I) from the mycelia of the fungal strain Paecilomyces sp. BM2419 upon irradiation with a halogen lamp the saintopin extracts dissolveld in 90% aqueous pyridine, and was finally purified by preparative HPLC.

合成路线图解说明: Title compound was generated during the extraction of saintopin (I) from the mycelia of the fungal strain Paecilomyces sp. BM2419 upon standing for several days the saintopin extracts dissolveld in DMSO, and was finally purified by C18 solid extraction, followed by preparative HPLC.