-药物合成数据库

【药物名称】

化学结构式(Chemical Structure):

参考文献No.	478972
标题:	1,2-Benzisothiazol-3-one 1,1-dioxide inhibitors of human mast cell tryptase
作者:	Combrink, K.D.; G黮geze, H.B.; Meanwell, N.A.; Pearce, B.C.; Zulan, P.; Bisacchi, G.S.; Roberts, D.G.; Stanley, P.; Seiler, S.M.
来源:	J Med Chem 1998,41(24),4854

合成路线图解说明: The title compound was prepared by condensation of 2-(bromomethyl)-1,2-benzisothiazol-3(2H)-one S,S-dioxide (I) with N-(benzyloxycarbonyl)-5-aminopentanoic acid (II) in the presence of K2CO3.