【药物名称】F-12682
化学结构式(Chemical Structure):
参考文献No.37964
标题:Novel aromatic piperazines derived from substd. cycloazanes, method for preparing same, pharmaceutical compsns., and use thereof as drugs
作者:Jorand-Lebrun, C.; Pauwels, P.; Chopin, P.; Marien, M.; Halazy, S. (Pierre Fabre M閐icament)
来源:JP 2000505795; WO 9728141
合成路线图解说明:

By condensation of 1-(2-phenylethyl)piperazine (I) with 4-methoxy-3-(4-methyl-1-piperazinyl)aniline (II) and triphosgene by means of triethylamine in dichloromethane.

参考文献No.479599
标题:Synthesis and pharmacological studies of a new 5HT1B/1D receptors inverse agonist
作者:Jorand-Lebrun, C.; et al.
来源:15th European Federation for Medicinal Chemistry International Symposium on Medicinal Chemistry (Sept 6 1998, Edinburgh) 1998,Abst P.162
合成路线图解说明:

By condensation of 1-(2-phenylethyl)piperazine (I) with 4-methoxy-3-(4-methyl-1-piperazinyl)aniline (II) and triphosgene by means of triethylamine in dichloromethane.

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