NNC-92-1687-药物合成数据库

【药物名称】NNC-92-1687

化学结构式(Chemical Structure):

参考文献No.	483116
标题:	Discovery and structure-activity relationship of the first non-peptide competitive human glucagon receptor antagonists
作者:	Madsen, P.; Knudsen, L.B.; Wiberg, F.C.; Carr, R.D.
来源:	J Med Chem 1998,41(26),5150

合成路线图解说明: Title compound was synthesized by S-alkylation of 2-mercaptobenzimidazole (II) with a-chloro-3,4-dihydroxyacetophenone (I) in refluxing acetonitrile.