【药物名称】NPS-2390
化学结构式(Chemical Structure):
参考文献No.39449
标题:Metabotropic glutamate receptor antagonists for treating central nervous system diseases
作者:Moe, S.T.; Smith, D.L.; Sheehan, S.M.; Shcherbakova, I.; Travato, R.; Walton, R.; Barmore, R.; Stormann, T.M.; DelMar, E.G.; VanWagenen, B.C. (NPS Pharmaceuticals, Inc.)
来源:EP 1037878; JP 2001524468; WO 9926927
合成路线图解说明:

The title amide has been obtained by condensation of adamantan-1-amine (I) with quinoxaline-2-carbonyl chloride (II) in pyridine.

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