【药物名称】SWR-0315Na(oxalate salt), SWR-0342SA
化学结构式(Chemical Structure):
参考文献No.38539
标题:Phenoxyacetic acid derivative
作者:Totani, H.; Masagaki, T.; Kakita, T.; Sawada, K.; Otsubo, Y.; Kiso, T.; Namikawa, T. (Sawai Pharmaceutical Co., Ltd.)
来源:JP 11035534
合成路线图解说明:

Hydrazinolysis of phthalimido derivative (I) afforded amine (II), which was condensed with (phenoxymethyl)oxirane (III) in boiling isopropanol to give amino alcohol (IV). After hydrolysis of the tert-butyl ester group of (IV), the resultant compound (V) was converted to the title hemioxalate salt upon treatment with oxalic acid.

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